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These authors also demonstrated that the elimination of Nrf2 only affected NQO1, among different Nrf2-regulated phase II enzymes, leaving it an open question whether Nrf2-mediated neuroprotection is a key mechanism to prevent ALS neurodegeneration [168]

Neurology 51 , 15621566 (1998)

Deep brain stimulation of the subthalamic nucleus vs

Since ferroptosis involves free radical-mediated lipid peroxidation, we hypothesized that enteral administration of the radical scavenger butylated hydroxytoluene (BHT) might slow down or even prevent the development of AD-related symptoms in an in vivo animal AD model