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178,179 Additionally, cAMP can activate Rap1 through EPAC (Exchange Protein directly Activated by cAMP), 180,181,182 which is involved in regulating insulin secretion

It is also worth noting that Vitamin B12 injections do not need the digestive system to be absorbed by the body, which makes them particularly beneficial for those who suffer from vitamin B12 deficiency as a result of problems in the digestive system, or as a result of a lack of intrinsic factor in the stomach.

Not having enough B12 can make migraine worse

Disclosure of interest: Kirsi Rantanen:nothing to disclose, Liisa Verho:nothing to disclose, Aino Korhonen:nothing to disclose, Anna Richardt:nothing to disclose, Karoliina Aarnio: nothing to disclose, Hannele Laivaara:nothing to disclose, Minna Tikkanen:nothing to disclose, Mika Gissler:nothing to disclose, Petra Ijs:nothing to disclose