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Such a metabolic recalibration is more than just an energy-generating mechanism for ATP synthesis

Robinson P, Sparrow AJ, Psaras Y, Steeples V, Simon JN, Broyles CN, Chang YF, Brook FA, Wang YJ, Blease A, Zhang X, Abassi YA, Geeves MA, Toepfer CN, Watkins H, Redwood C, Daniels MJ

Applying it universally is pattern-matching, not pharmacology

10.1038/nature02625 Nature 35 EndohT

For instance, the aberrant methylation of the zinc finger protein 577 ( ZNF577 ) gene has been proposed as a promising epigenetic biomarker for predicting clinical outcomes in LUAD patients