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In brief, the measurements were performed using a Shimadzu Prominence HPLC (Shimadzu, Reinach, Switzerland) coupled to a SCIEX 4000 QTrap mass spectrometer (AB Sciex, Darmstadt, Germany) and a PAL autosampler (CTC Analytics, Zwingen, Switzerland)

The GLUD1 protein is a mitochondrial enzyme that converts L-glu to 2-oxoglutarate

Comparing the former version of these documents and the 2026 updated ones, the major changes are: Further examples or clarifications have been added to the following substance classes to help athletes and their entourage better identify prohibited substances: S1