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Conversely, cancer cells were less sensitive to inhibitors of cystine uptake (for example, erastin) and the thioredoxin pathway (for example, auranofin, aurothioglucose and PX-12) (Fig

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doi: 10.1016/S0140-6736(21)00392-5 4 KosekEClauwDNijsJBaronRGilronIet al

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This cell death process cannot be inhibited by regulatory cell death specific inhibitors, but antioxidants and chelators can prevent and reverse this process