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Emerging studies have demonstrated robust predictive accuracy well before clinical diagnosis, offering pathways to early intervention, patient stratification, and enrollment in disease-modifying trials

Your body usually has plenty of glycine and glutamic acid, but it can run low on cysteine

HIF-1 is a major regulatory factor in the hypoxia response, playing a critical role in the regulation of the glycolysis process

These changes may trigger the release of a variety of astrocyte-derived signaling modulators, which may control neuronal activity

Interestingly, the hierarchical clustering analysis of DAPs in five comparison groups showed that DAPs of T2/T1, T3/T1 (Additional file 5: Table S5), T4/T1, T4/T2 (Additional file 6: Table S6) and T4/T3 had different expression patterns (Fig