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Investigating the mitochondrial targeting capacity of polyphenols, their role in functional regulation, and their ability to modulate oxidative stress, along with exploring novel technologies and strategies for modifying polyphenol compounds and their formulations, holds promise for providing new avenues for the treatment of neurodegenerative diseases

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10.1093/hmg/ddu409 Summary Keywords amyotrophic lateral sclerosis (ALS), TDP-43, mitotoxicity, liquid-liquid phase separation (LLPS), endocytosis, frontotemporal lobar degeneration (FTLD), prion, ALS therapeutics Citation Prasad A, Bharathi V, Sivalingam V, Girdhar A and Patel BK (2019) Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis

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(Learn more about Team Human Powered Potential here.) 13-time GRAMMY-winning artist and headliner Stevie Nicks played hits including, Gypsy, Stand Back, Rhiannon, Landslide, Edge of Seventeen, and Stop Draggin' My Heart Around. Special musical guest Maggie Rogers joined Stevie Nicks and Michael J