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The DNA fragments were purified, end-repaired, and ligated with SMRTbell sequencing adapters following the manufacturers instructions (Pacific Biosciences, CA)

doi: 10.1186/1559-0275-11-40 244 YangJIKongTWKimHSKimHY

However, IKK deficient mice die on 14 th day of gestation because of massive apoptosis of hepatocytes, therefore, these clinical trials have to be terminated [38, 121]

Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation