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While the greater amount of cellular reduced GSH is found in the cytosol and mitochondria, the endoplasmic reticulum becomes a reservoir of small concentrations of the oxidized form of GSH (GSSG)

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While ROS are essential for pathogen clearance, excessive and unregulated production leads to widespread cellular and tissue injury (Figure 3) (Mantzarlis et al., 2017)

Its also approved for use in wound dressings due to its ability to form a gel