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Back to Journals Diabetes, Metabolic Syndrome and Obesity Volume 18 Marmelosin Protects Against Metabolic Disturbances in High-Fat Diet and Streptozotocin-Induced Diabetes Authors Alenezi SK , Alharbi KS , Alsahli TG, ALQahtani R, Afzal M , Sharma KK, Sayyed N Received 9 October 2025 Accepted for publication 20 November 2025 Published 30 December 2025 Volume 2025:18 Pages 47694785 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Rebecca Baqiyyah Conway Sattam Khulaif Alenezi, 1 Khalid S Alharbi, 1 Tariq G Alsahli, 2 Reem ALQahtani, 3 Muhammad Afzal, 4 Krishana Kumar Sharma, 5 Nadeem Sayyed 6 1 Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, Al Qassim, 51452, Saudi Arabia

When examining the inclusion of Ent2 in the context of this Clathrin double mutant, we observe an increased inclusion in Abp1+ events, attributable to diminished binding from Ent1, which has now lost its main binding site

Adults under 30 used supplements more and preferred multi-component products, whereas older adults showed the highest rate of non-use and favored L-carnitine for energy and muscle preservation

Leveraging the relationship between macrophage polarization phenotypes and iron metabolism, therapeutic targeting of TAMs within the TME represents a promising anti-tumor strategy (2)