is inducing glutathione pro-oxidant response and accelerated ferroptosis caused by synergetic Au(I) release in hypercarbon-centered gold(I) cluster prodrugs Oxidative stress: the big issue

Given that these basal metabolic processes are putatively present in both groups of this study and no indications exist that these could play a role in tinnitus pathophysiology, we surmise that this possible confounder can be ruled out in the presented results and the found differences between groups represent true effects

How do you distinguish a back-of-the-pack runner on a blood-pressure medication that theoretically requires a medical exemption from a competitive age-group contender seeking an advantage

Liu H, Patel MR, Prescher JA, Patsialou A, Qian D, Lin J et al

xCT inhibition increases sensitivity to vorinostat in a ROS-dependent manner

In the context of ferroptosis, ChaC1 degradation of GSH enhances susceptibility to ferroptosis under cystine starvation conditions (Wang et al., 2019)