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Description

Antibody drug conjugates (ADCs) are an emerging class of antitumor agents that selectively target tumor cells and deliver concentrated cytotoxic payloads through an antibody-mediated process, effectively sparing normal tissue

Kirihara, M

Behav Genet

In accord with this embodiment, a polynucleotide may be a circular molecule comprised of an intermediate or central region, which region is flanked on a 5' side by a 5' flanking region (which, for the purpose of end-selection, serves in like manner to a 5' terminal region of a non-circular polynucleotide) and on a 3' side by a 3' terminal region (which, for the purpose of end- selection, serves in like manner to a 3' terminal region of a non-circular polynucleotide)