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Abstract Reactive oxygen species (ROS) and oxidative stress have been implicated in cochlear injury following loud noise and ototoxins

This often leads to faster and more reliable results, especially for those with absorption issues

One of the reasons that Acs is an attractive target for the treatment of human disease is that under normal physiological conditions, ACSS2 and its substrate, acetate, are minor contributors to the overall pool of AcCoA in human or mammalian cells 13,14