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Emerging role of the cGAS-STING signaling pathway in autoimmune diseases: Biologic function, mechanisms and clinical prospection

The results of the current study for lowered zinc concentrations could be explained on the basis that either it is excessively being utilized in providing antioxidant defense mechanism or there is some defect in the absorption/ metabolism of zinc in toxic conditions created by protein deficiency

This approach elevates mechanistic toxicology from a downstream regulatory hurdle to an indispensable, a priori design tool

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Additionally, antibody-based biomarkers hold promise for predicting treatment outcomes and identifying individuals at increased risk of disease relapse, thereby informing clinical decision-making, and improving patient outcomes