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Description

In normal cases, PINK1 is degraded by healthy mitochondria, but when mitochondria become dysfunctional or damaged, PINK1 accumulates on their outer membranes, recruiting Parkin to mark the defective organelles for autophagic degradation

10.18632/aging.100673 8 CampisiJ

and Kudo, I

(Kava) Chem

With the rapid development of lipidomics technologies, especially the application of MS-based high-throughput analysis platforms and multivariate statistical methods, the identification and quantification of these lipid markers have become feasible