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Rapamycin, which induces autophagy through the inhibition of mTORC1, and wortmannin, which inhibits autophagy through inhibition of phosphatidylinositol-3-kinase (PI3K), were used as controls (Powis et al., 1994

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To view a copy of this license, visit About this article Cite this article Ibrahim, I.M., Wu, H., Ezhov, R

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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity