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ClinicalTrials.gov ID NCT05703074 Haukeland University Hospital, et al

As research in this field progresses, it is essential to adopt a multidisciplinary approach, integrating insights from nutrition, toxicology, molecular biology, epidemiology, agricultural science and public health

This group described decreased activity of nicotinamide N-methyltranserase (NNMT), an enzyme that catalyzes the N-methylation of nicotinamide and other pyridines in the CSF of younger PD patients compared with younger controls, and a trend toward decrease with aging in PD patients (Aoyama et al., The results of studies on neurotoxins related with the risk for PD are based on small series and are not conclusive