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De-acetylation is an ordinary occurrence in cells, and once in the cells, S-acetyl-glutathione is naturally de-acetylated to glutathione

19 Although the mechanisms underlying endothelial dysfunction are multifactorial, a growing body of evidence suggests that increased ROS production contributes considerably to this phenomenon in several ways

IUBMB Life 65 , 358365 (2013)

LRRK2 in Parkinsons disease: Protein domains and functional insights

This disruption in the phagocytic clearance of apoptotic cells will likely cause chronic inflammation and weakened immune responses, potentially worsening tissue damage during infections