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Proc Natl Acad Sci USA 84:63406344

3xTg mice have consistently been shown to have impairments in hippocampal-dependent tasks such as Barnes Maze and NOR with memory deficits becoming apparent as early as 4-6 months of age and growing more severe with increasing age 13,59

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies

Icariside I enhances beneficial gut bacteria, upregulates immune cells, and inhibits melanoma (B16-F10) cell growth [760, 761]

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