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doi: 10.1007/s00424-022-02752-1 73 GuptaNMiyauchiSMartindaleRGHerdmanAVPodolskyRMiyakeKet al

One h after ulcer induction, omeprazole (20 mg/kg/day), NPW (0.1 g/kg/day) or saline was intraperitoneally administered

The paradigmatic evolution of CKD pathogenesis research has witnessed a transformative shift from reductionist single-organ conceptualization toward sophisticated multi-systemic network modeling, epitomized by the revolutionary gut-kidney axis hypothesis (Tsuji et al., 2024