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Cohen PL, Cheek RL, Hadler JA, Yount WJ, Eisenberg RA

[,] MDA level was decreased with the use of topical aescin, topical clobetasol, the combination of topical aescin and clobetasol, and oral aescin, while SOD level was significantly increased by the use of aescin both topically and orally with the greatest increase was noticed in the combination group

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Not all melanomas have a color or are raised above the skin surface