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The previous studies report that administration of sitagliptin increases the C-peptide in serum which is essential for the synthesis of insulin, the current study shows that combination therapy has the potential to restore C-peptide

Platelet Rich Plasma (PRP) is a concentrate of platelet-rich plasma protein derived from the whole blood after it has been processed by spinning in a centrifuge to remove the red cells

The transport protein is currently unknown, but is generally believed to be organic ion transporting polypeptide (OATP) transporter

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Acknowledgements The authors would like to thank Mr