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One commenter noted that the payment change for hepatitis B vaccines in RHCs and FQHCs will provide easier access to those vaccines, and thus improve quality of life, for Medicare enrollees and those with disabilities who live in rural areas where accessing primary care is difficult

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That depth of evidence is what FDA requires for approval

B12 injections and how they work Vitamin B12 injections are administered intramuscularly or subcutaneously to treat or prevent deficiency