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10.1002/j.1551-8833.1983.tb05122.x 25 KadriS

Ubiquitin is a key covalent modification mechanism, which covalently links ubiquitin peptide chains containing 76 amino acids to lysine residues of histones through the continuous action of the E1 activating enzyme, E2 binding enzyme and E3 ligase (6)

Increase in oxidized NO products and reduction in oxidized glutathione in cerebrospinal fluid from patients with sporadic form of amyotrophic lateral sclerosis

In an experimental model a strong VlsE IgG antibody response was apparent by the fourth week of infection, indicating that VlsE is expressed during early stage of infection