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Emerging regulatory mechanisms and functions of biomolecular condensates: implications for therapeutic targets

J Diabet Complications 2004

Potential clinical relevance While current PH therapies (i.e., prostacyclins, phosphodiesterase inhibitors, calcium channel blockers, endothelin receptor antagonists, or soluble guanylate cyclase stimulators) focus primarily on alleviating vasoconstriction as a symptomatic approach (215), the long-term therapeutic goal is to shift towards targeting mechanisms of disease onset and progression, including vascular remodeling and inflammation (215)

Thus, investigations of benfotiamine for diabetic complications are still under way