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Conventional treatments for chronic constipation frequently demonstrate suboptimal long-term efficacy, with patients typically needing to try multiple medications before finding an effective regimen (Rao et al., 2016)

Free Radic Res 1999, 31: 273300

Its suggested to give this dose daily or every other day for one to two weeks to effectively address the deficiency

Exploring the efficacy of pulsed electric fields (PEF) in microbial inactivation during food processing: a deep dive into the microbial cellular and molecular mechanisms