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Unsuspected task for an old team: succinate, fumarate and other Krebs cycle acids in metabolic remodeling

Hydrolyzed cisplatin then enters the nucleus where it crosslinks DNA purine residues and subsequently forms adducts and consequential damage in the DNA strand, which eventually leads to apoptosis in cancer cells (Fig

I just dont get why this has happened as I have been self injecting B12 every month no problem for a long time until now, although I have had similar problems in the past when trying to get my levels right (that I have posted about on here)