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As many as one-third of patients with one of the most dreaded outcomes of B12 deficiency, subacute combined degeneration of the spinal cord, had normal or even elevated levels of B12 in their blood

The April 2026 FDA action removes them from the Category 2 restricted compounding list effective April 23, 2026, and the FDAs Pharmacy Compounding Advisory Committee will review their compounding eligibility under 503A at its July 23-24, 2026 meeting

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This is where the cyanocobalamin component was intended to help