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403 Studies have also reported that selenium protects the BBB from ischemia-reperfusion injuries associated with PI3K/mTOR/AKT signaling pathway activation, which is possibly related to autophagy inhibition

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Cytotoxicity was assessed by measuring lactate dehydrogenase release as previously described [15] and CSE treated cells under conditions tested did not have changes in cell viability that were statistically significantly different from controls and was greater than 85%