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Sulfasalazine: pharmacology, clinical use, toxicity, and related new drug development

Abstract Systemic lupus erythematosus (SLE) patients exhibit depletion of the intracellular antioxidant glutathione and downstream activation of the metabolic sensor, mechanistic target of rapamycin (mTOR)

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In line with this, ELISA results revealed that anti-NIP IgG1 REW engages C1q more efficiently than WT when captured on different cognate antigen densities (Fig