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[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Pitt JM, Marabelle A, Eggermont A, Soria JC, Kroemer G, Zitvogel L

These models have provided a service in the development of therapies for Graves disease, including immune-modulatory treatments targeting autoimmune components of the disease, and thus laid the groundwork for therapeutic advances in human patients (Kahaly 2020)

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The GSH tripeptide (- L-glutamyl-L-cysteinyl-glycine), the most abundant water-soluble non-protein thiol in the cell (110 mM) is fundamental for life by (a) sustaining the adequate redox cell signaling needed to maintain physiologic levels of oxidative stress fundamental to control life processes, and (b) limiting excessive oxidative stress that causes cell and tissue damage

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