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The processes classically thought to underlie this metabolic shift include the Randle cycle and changes to gene expression

Holt PG, Strickland DH, Wikstrm ME, Jahnsen FL

Non-Coding RNA Res (2025) 10:639

Jharap B, Seinen ML, De Boer NKH, Van Ginkel JR, Linskens RK, Kneppelhout JC et al

As DAF-16 and SKN-1 themselves are under redox regulation 18,19 , the dietary thiols could deactivate these transcription factors by reducing their redox sensitive partners