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These structures distinguish FMR1 from other CpG islands containing promoters (Ginno et al., 2012, 2013) and could finally trigger repeat instability and hypermethylation (Loomis et al., 2014)

The highest proportion of patients meeting these criteria was observed in the JNJ-3989 (200mg) dual-therapy group, reaching 19%

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It helps maintain left ventricular ejection fraction (LVEF) and heart function, increases prosurvival genes like Bcl-2, and boosts antioxidant defenses