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doi: 10.1016/j.jtho.2023.04.021 110 ShoushtariANPowellDJ

Histoplasma capsulatum -(1, 3)-glucan blocks innate immune recognition by the -glucan receptor

Involvement of acetaldehyde for full protection against alcoholism by homozygosity of the variant allele of mitochondrial aldehyde dehydrogenase gene in Asians

852A is also an imidazoquinoline TLR7/8 agonist, which has previously been tested in multiple tumors types (including renal cell carcinoma, melanoma, lung cancer, hematologic malignancies, breast cancer, ovarian cancer, and cervical cancer), showing acceptable tolerability, evident immune stimulation, and clinical benefit in some patients (288291)