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The simultaneous upregulation of TIMP-1 and TIMP-2, the natural inhibitors of MMPs, suggests a regulatory influence of GHK-Cu on the balance between matrix synthesis and matrix degradation (Pickart et al., 2015)

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doi: 10.3350/cmh.2023.0125 19 PaulBLewinskaMAndersenJB

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After (1) cell entrance, the nitro group is reduced, leading to (2) the formation of reactive radicals interacting with (3) different cellular components 13 (Fig