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Inducible and constitutive beta-defensins are differentially expressed in Crohn's disease and ulcerative colitis

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[PubMed: 25485909] 156

594 The OPTION-DM study determined which monotherapy and combination therapy of amitriptyline, duloxetine, and pregabalin are the most clinically efficacious

A switch from L-peptides to DRI peptides will not change this scenario for the S-shaped A 42 fibrils, however, it will still lead to a smaller number of hydrogen bonds in the DRI-fibril than seen in the L-fibril