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Assaying for redox markers in response to nicotine in fibroblasts as an index of oxidative stress is a pertinent area for investigation, with regard to potential oxidative effects of nicotine and its modulation by the anti-oxidant glutathione

It has been reported that hydrogen peroxide induces the nuclear localization of MT in culturing BALB 3T3 cells, depending on the cell cycle [154,155]

doi: 10.1016/j.copbio.2008.06.004

One of the most concerning consequences of excessive glutamate activity is excitotoxicity, a process whereby overstimulation of glutamate receptors, particularly NMDA receptors, leads to neuronal injury or death

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