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2013;110:E115261

Its clinical development was halted, so there is no completed pivotal trial, no approved label, no reviewed dose, and no regulatory safety determination

Holocaust Center of the United Jewish Federation of Pittsburgh, accessed November 24, 2009

In its discovery-to-proof-of-concept work, it activated both receptors in vitro , improved glucose-dependent insulin secretion and glucose tolerance in animals, and in early human studies lowered fasting glucose and body weight