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Perekopskiy D, Kiyatkin EA

Detection of mitochondrial superoxide with MitoSOX The production of superoxide in mitochondria was visualized with MitoSOX Red (Life Technologies)

Among useful antioxidants in this regard are reducing agents, oxygen/free-radical scavengers, and chelating agents

In light of this, high-dose IVC has re-emerged as a potent anti-cancer agent over the past two decades, with several phase I and a few phase II clinical trials reporting high tolerability and safety with promising signs of efficacy in the treatment of various cancer types, either as monotherapy or as a combination therapy [14,15,16]