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Significant progress has been made in both diagnostics and therapeutics

Heme oxygenase-1 induction may explain the antioxidant profile of aspirin

Also, Bihaqi and Zawia ( APP , Tau and GSK3 genes was reported in post-mortem brains (Iwata et al., APP could be mediated by the oxidation of guanine (8-oxdG) (Zawia et al., 2009)

Resistance to Drugs and Oxidative Stress.

Taken together, the findings of clinical studies investigating the prevention of chronic diseases such as cancer, cardiovascular and metabolic diseases, and neurological disorders do not support the preventive effect of vitamin E supplementation