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An introduction glutamate dehydrogenase physiology In humans, glutamate dehydrogenase (GDH) is found in the mitochondrial matrix and is mainly expressed in the pancreas, liver, kidney, and brain

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Protease activation in drug-induced apoptosis in CLL

These data suggest that MYCN -amplified neuroblastoma cells with very high levels of MYCN are sensitive to a reduction of the intracellular cysteine pool by simultaneous inhibition of cystine import and cysteine synthesis via transsulfuration

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