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doi: 10.1016/S0140-6736(72)90676-9 3 RuwendeCKhooSCSnowRWYatesSNKwiatkowskiDGuptaSet al

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[8] also reported elevated oxidative stress and inflammation in lipedema tissue, and our metabolomic data support the existence of a dysregulated redox environment potentially sustained by aberrant AKT1 activation