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Gholamreza Raissi et al., 2022 used ultrasound guidance for sacroiliac joint injections, targeting a deep joint [62]

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The above studies demonstrated that SCU acts on the TLR4/MyD88/NF-B signal pathway to exert antihypertensive and antidiabetic effects (Figure 9)

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Another study revealed that 77% of men and 80% of postmenopausal women developed organ dysfunction under choline deprivation, while less than half of premenopausal women did, highlighting the possible protective role of estrogen in choline deficiency