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Description

(US Patent 8598118) characterized hepatocyte growth factor mimics as therapeutic agents and established the mechanistic basis for Dihexas development

Chen YM, Fan H, Huang J, Shi TS, Li WY, Wang CN, et al

Toxicol Pathol

Journal of Pharmacology and Experimental Therapeutics via PubMed (PMID 25187433), 2014 AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway (animal study not human evidence)