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Open fractures that break through the skin carry a significant risk of bacterial contamination, and infected bone heals poorly or not at all

Common contributing factors include poor posture, sedentary lifestyle, improper lifting technique, excess body weight, and genetic predisposition

The FDA reaffirmed the decision on December 19, 2024

I also encountered Covid arm (redness and swelling)

Although subgroup analyses were performed, these are exploratory and may be underpowered, and residual confounding cannot be excluded MRI assessment relied on semi-quantitative MOAKS scoring rather than volumetric BML measurement, which may limit sensitivity to subtle structural changes