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This approach can look like a blood sugar-balancing eating plan, strength training, bioidentical hormone replacement therapy (BHRT), and targeted supplements, such as berberine

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Introduction Endoplasmic reticulum (ER) stress, which is well known as the accumulation of unfolded proteins in ER lumen caused by the increase of protein synthesis or multiple conditions, and ER responds to ER stress by activating the unfolded protein response (UPR), an adaptive intracellular signal to cope with ER stress and help to sustain cell survival and normal functions (1)