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Individuals with kidney disease, heart conditions, or certain metabolic disorders may not be suitable candidates, which is why a health screening conversation prior to treatment is standard practice

Functionalization with targeting ligands further enhances uptake by neurons or glia, enabling precise regional delivery

In patients with IBD, deficits in both the number and function of Tregs lead to immune dysregulation and exacerbation of inflammation [363]

Stable for months to years when frozen [13]

4 Role of piperine in targeting cancer hallmarks 4.1 Role of piperine in genomic instability Genomic instability is a fundamental hallmark of all cancer cells, enabling malignant cells to accumulate mutations and evade regulatory mechanisms