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Mrp4 and Mrp5 share only 35% identity with Mrp1 and function as nucleotide transporters

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Studies of stored RBCs in blood bank conditions also reported the recruitment of Prx2, CAT and GPx to the RBC membrane due to OS modifications resulting from the metabolic stress of long-term erythrocyte storage [93, 97]

In conclusion, our study revises the traditional view of GSH as a global protective antioxidant against protein oxidation under physiological condition and demonstrates that GSH depletion through enhanced degradation leads to selective protein oxidation

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