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Furthermore, in our recent study, we performed untargeted metabolomics and miRNAseq on mild and sever AMN and age and sex-matched healthy human plasma and observed a significant clinical correlation for 7-alpha-hydroxy-3-oxo-4-cholestenoate (7-HOCA), dehydroepiandrosterone sulfate (DHEA-S), hypoxanthine, and miRNA-4325p [94]

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Within the barrel-stave model, the aNDB molecules are initially oriented parallel to the membrane but eventually inserted perpendicularly in the lipid bilayer (Hegde et al., 2022) (Figure 4)

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(No abstract available)