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However, some users report better tolerability with tirzepatide, possibly due to the GIP component modulating GLP-1 effects

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Data were expressed as permeability (Papp) calculated using the following formula: where dQ/dt, rate of permeation C 0 , initial concentration of compound A, area of monolayer (0.11 cm 2 ) Efflux Ratio (R e ) was calculated using the formula: 5.2

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